IARPA/SRC Workshop on DNA-based Massive Information Storage (invitation only)
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- Date:
- Wednesday, April 27, 2016, 7:30 a.m. — Thursday, April 28, 2016, 4 p.m. ET
- Location:
- Hyatt Arlington, 1325 Wilson Boulevard, Arlington, VA, United States
- Event ID:
- E006043
The workshop seeks to identify research directions that may support the development of DNA-based massive information storage technologies.
Wednesday, April 27, 2016 - Senate Ballroom, Second Floor | ||
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7:30A - 8:00A |
Workshop Check-in |
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8:00A - 8:30A | Welcoming Remarks |
Jason Matheny / IARPA |
Session I - Nucleic Acid Memory for Massive Storage: Fundamentals and Application Perspectives (Session Chair: David Markowitz / IARPA) | ||
8:30A - 10:30A | Keynote: Next-Generation Digital Information Storage for DNA | George Church / Harvard - USA |
Roundtable / Open Mic Discussions: Karin Strauss / Microsoft - USA |
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10:30A - 10:45A | Break | |
Session II - DNA Sequencing Technologies: Current Status and Future Directions (Session Chair: Steve Hillenius / SRC) | ||
10:45A - 12:45P | Keynote: DNA Chip in Handsets | Mostafa Ronaghi / Illumina - USA |
Roundtable / Open Mic Discussions: Steve Turner / Pacific Biosiences - USA |
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12:45 - 2:00P | Lunch (on your own) | |
Session III - Toward a Practical DNA Hard Drive: Synthesis of Digitally Encoded Polymers (Session Chair: John Cumbers / SynBioBeta) | ||
2:00P - 4:00P
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Keynote: Design and Synthesis of Digitally Encoded Polymers that can be Decoded and Erased | Jean-François Lutz / Inst. Charles Sadron - France |
Roundtable / Open Mic Discussions: Sriram Kosuri / UCLA - USA |
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4:00P - 4:15P |
Break |
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Session IV - Operational Aspects of DNA-based Storage System (Session Chair: Brian Brameltt / Intel) | ||
4:15P - 6:15P | Keynote: A Rewritable, Random -Access DNA-Based Storage System | Olgica Milenkovic / U Illinois - USA |
Roundtable / Open Mic Discussions: Victor Zhirnov / SRC - USA |
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Thursday, April 28, 2016 | ||
Session V - Breakout Group Discussions | ||
Morning Breakout - we will hold two rounds of parallel breakout sessions on three technical areas: 1) DNA Synthesis (Facilitator: Mark Bathe) - Senate Ballroom, Second Floor 2) DNA Sequencing (Facilitator: John Kasianowicz) - Marshall Room, Lobby Level 3) Operational Aspects of DNA-based Storage System (Facilitator: Luis Ceze) - Douglas Room, Lobby Level |
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9:30 - 10:30A | Breakout Round 1 - Assigned Seating (attendees will be notified of their group assignments prior to Day 2) | |
10:30A - 11:00A | Break | |
11:00A - 12:00P | Breakout Route 2 - Free Choice (continue your first round discussion or joint a new one) | |
12:00: - 1:30P | Lunch (on your own) | |
1:30 - 2:15P | Breakout Group Reports (15 minutes each) - Senate Ballroom, Second Floor | |
Session VI - Research Needs and Potential Responses (Session Chair: Ralph Cavin / SRC) | ||
This session will examine technology gaps and gating research issues critical to enabling the future DNA storage systems. The goal is to identify promising future directions for university research from the perspectives of industry, university and government stakeholders. | ||
2:15P - 3:30P |
Roundtable / Open Mic Discussions: (Senate Ballroom, Second Floor) Mitra Basu / NSF - USA |
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3:30P - 4:00P | Closing comments / Adjourn |
Discussion Framework
Purpose
The explosion of data and the potential to extract greater insight from rich data sources is driving challenges and opportunities for the future of information technology . One major challenge is the need for storage technologies that scale without imposing prohibitive power and cost requirements. To address this need, the proposed workshop seeks to identify research directions that may support the development of DNA-based massive information storage technologies. This is motivated by two key developments:
- Recent work has shown that global demand for conventional silicon-based memory is growing exponentially, while silicon production is growing only linearly. This disparity guarantees that silicon-based memory will become prohibitively expensive for Zetta-scale “big data” deployments within two decades.
- Recent studies by three distinct research groups have demonstrated proof-of-concept that DNA can be used to support scalable , random-access and error-free information storage . These advances now make DNA a very attractive potential alternative to silicon for information storage, because:
- DNA has an information storage density that is several orders of magnitude higher than any other known storage technology. In theory, a few tens of kilograms of DNA could meet all of the world’s storage needs for centuries to come.
- DNA can store information stably at room temperature for hundreds of years with zero power requirements, making it an excellent candidate for large-scale archival storage.
- With technology advances, DNA could be orders of magnitude cheaper to produce than wafer-grade silicon.
The growing demand for alternative storage technologies, coupled with recent major advances by a critical mass of researchers in the DNA storage field, suggests that practical DNA storage technologies capable of meeting the world’s needs may be achievable in five years. To explore this issue, this workshop will pose the following questions to attendees: What are the greatest barriers to achieving practically useful technologies for DNA-based massive information storage? What recent methodological advances in biology, microfluidics or other disciplines suggest this goal is achievable? What level of multidisciplinary coordination is required to achieve this goal? What tools or strategies will be the key to success?
Format
This is an invitation-only meeting where all attendees are expected to actively participate. The 2 -day workshop will be constructed to include selected overview presentations and panel discussions. It will encourage and enable interactions by allotting sufficient time for in-depth panel-participant interactions. Participants will be asked to identify capabilities may only be achievable through large, focused investment by an applied research agency.
Outcome
A detailed technical report will be generated resulting from the inputs gathered at the workshop that will be useful in describing promising research directions. Successful execution of the workshop goal will be used to inform the strategic funding priorities of the sponsors.
Venue
Hyatt Arlington
1325 Wilson Boulevard
Arlington, VA 22209
Phone: +1 (703) 525-1234
Room Block: IARPA SRC/DNA Workshop
Room Rate: $226/night + tax
Room Block Cut-off Date: April 1, 2016
Reservations: 1-888-421-1442, 402-592-6464 or https://resweb.passkey.com/Resweb.do?mode=welcome_ei_new&eventID=14862027
Transportation
From Ronald Reagan Washington National Airport (DCA)
- Taxi - taxi stands are located in the arrivals area near baggage claim in each terminal. Fare to the hotel is approximately $10
- Washington Metropolitan Area Transit Authority - Take the Metro Blue Line in the direction towards Largo Town Center, exit at the Rosslyn stop. After exiting, go up to the top level of the station, exit by the stairway to the right and our hotel is directly across the street.
Driving Directions
From Ronald Reagan Washington National Airport DCA (4.55 miles)
Merge onto George Washington Memorial Parkway North. Merge onto I-395 South toward Richmond. Merge onto VA-110 North / Jefferson Davis Highway via Exit 8B toward I-66 W / Rosslyn. Turn slight left to take the Wilson Boulevard ramp toward Rosslyn. Turn slight left onto Wilson Boulevard. Turn right onto Nash Street. Our hotel is immediately on the right.
From Washington Dulles International Airport IAD (24.47 miles)
Head West on I-195. Merge onto MD-295 South via Exit 2B toward Washington. Merge onto US-50 West / New York Avenue NE toward Washington (Crossing into the District of Columbia). Take I-395 South toward Tunnel (Crossing into Virginia). Merge onto VA-110 North / Jefferson Davis Highway via Exit 8B toward I-66 West / Rosslyn. Turn slight left to take the Wilson Boulevard ramp toward Rosslyn. Turn slight left onto Wilson Boulevard. Turn right onto Nash Street. Our hotel is immediately on the right.
From Baltimore-Washington International Airport (BWI) and Points North (37.28 miles or more)
Head West on I-195. Merge onto MD-295 South via Exit 2B toward Washington. Merge onto US-50 West / New York Avenue NE toward Washington (Crossing into the District of Columbia). Take I-395 South toward Tunnel (Crossing into Virginia). Merge onto VA-110 North / Jefferson Davis Highway via Exit 8B toward I-66 West / Rosslyn. Turn slight left to take the Wilson Boulevard ramp toward Rosslyn. Turn slight left onto Wilson Boulevard. Turn right onto Nash Street. Our hotel is immediately on the right.
Parking
Self Parking - Leave your car in our underground self-parking garage, just off Nash Street. No need to brave the elements. The garage is available daily for a fee of $23.00 per day.
Workshop Steering Committee
- David Markowitz / IARPA
- Jacob Vogelstein / IARPA
- Victor Zhirnov / SRC
- Ralph Cavin / SRC
- Steve Hillenius / SRC
- Celia Merzbacher / SRC
Name | Organization |
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Basu, Mitra | National Science Foundation |
Basu, Sankar | National Science Foundation |
Bathe, Mark | Massachusetts Institute of Technology |
Beal, Jacob | Raytheon Technologies |
Bramlett, Brian W. | Intel Corporation |
Carlson, Rob | Synthesis |
Castleman, Randy | Wyss Institute Biologically Inspired Engineering |
Cavin, Ralph K. | Consultant |
Ceze, Luis H. | University of Washington |
Church, George M. | Harvard Medical School |
Cumbers, John | SynBioBeta |
Faiers, Leslie | Semiconductor Research Corporation |
Grass, Robert N. | ETHZ - ETH Zurich |
Griswold, Kettner | Harvard Medical School |
Hansen, Ken | Semiconductor Research Corporation |
Hillenius, Steven | Semiconductor Research Corporation |
Hughes, William | Boise State University |
Kalhor, Reza | Harvard Medical School |
Kalil, Thomas | Office of Science and Technology Policy |
Kasianowicz, John | National Institute of Standards and Technology |
Kienker, Laura J. | U.S. Office of Naval Research |
Kosuri, Sriram | University of California, Los Angeles |
Leake, Devin | Gen9, Inc. |
Lee, Henry | Harvard Medical School |
Leslie, Terry | Micron Technology, Inc. |
Lu, Timothy | Massachusetts Institute of Technology |
Luan, Binquan | IBM Corporation |
Lutz, Jean-François | Institute Charles Sadron |
Markowitz, David A. | IARPA |
Matheny, Jason | IARPA |
Merzbacher, Celia I. | Semiconductor Research Corporation |
Milenkovic, Olgica | University of Illinois at Urbana-Champaign |
Palla, Mirko | Wyss Institute Biologically Inspired Engineering |
Peck, Bill | Twist Bioscience |
Robertson, Joseph | National Institute of Standards and Technology |
Ronaghi, Mostafa | Illumina, Inc. |
Sayir, Jossy | European Bioinformatics Institute |
Strassmann, Steve | Harvard Medical School |
Strauss, Karin | Microsoft Corporation |
Turner, Stephen | Pacific Biosciences of California, Inc. |
Varshney, Usha | National Science Foundation |
Vogelstein, Jacob | IARPA |
Wallach, David | Semiconductor Research Corporation |
Wegrzyn, Renee | DARPA |
Whitman, Lloyd | Office of Science and Technology Policy |
Zaaijer, Sophie | The New York Genome Center |
Zhirnov, Victor V. | Semiconductor Research Corporation |